According to the North America Menopause Society (NAMS), every woman who survives the middle-age stage of life will experience menopause, which usually starts between 40 and 58 years. The fundamental mechanism of menopause undergoes activities of the brain (hypothalamic-pituitary-ovarian (HPO) axis), a series of changes as a woman traverses through menopause. The primary driver of change is ovarian follicular depletion, which begins even before birth and results in a progressive, exponential loss of follicles over a woman's lifetime, characterized by changes in patterns of the menstrual cycle and a decrease in hormone levels. The menopause process symptoms affect body composition, including hot flashes, night sweats, flushing, vaginal atrophy, insomnia, other sleeping difficulties, increase in cardiac problems, bone depletion (osteoporosis), mood swings, and psychosocial well-being.